Bionic Biologics with human impact
Our interdisciplinary team of scientists and entrepreneurs is developing novel Bionic Biologics™ in the heart of Chicago. Our mission: develop therapeutics for the highest-impact disease targets, so millions of patients have better options. Are you with us?
Open positions
ABOUT
Grove Biopharma is a biotechnology company pioneering its proprietary Bionic Biologics™ platform to develop novel therapies targeting intracellular protein-protein interactions. Bionic Biologics represent a novel therapeutic modality that integrates principles of biologic and synthetic design to create customizable protein-scale molecules . This innovative platform enables the targeting of well-validated yet previously intractable disease drivers, unlocking new possibilities for therapeutic intervention.
Job Description
We are seeking an experienced R&D Project Manager to oversee and coordinate all aspects of preclinical drug development through IND filing. The project manager will be responsible for managing detailed project timelines for both internal scientific teams and external CROs, and ensuring projects are delivered on-time and within budget. The ideal candidate will be able to proactively identify and resolve potential risks to avoid project delays and will also be well-versed in regulatory requirements in order to facilitate a smooth IND filing process. This is a critical role within our organization, requiring strong project management skills, scientific expertise, and the ability to drive complex projects to successful outcomes.
Key Responsibilities
- Oversee and manage all activities related to the preclinical development of drug candidates to enable successful IND filings.
- Develop and maintain detailed project timelines, tracking progress against key milestones, and ensuring project teams adhere to critical deadlines.
- Coordinate and manage relationships with contract research organizations (CROs) and other external partners, including contract negotiations and ensuring that deliverables are provided on time.
- Collaborate closely with internal scientific team and external partners to ensure seamless communication, alignment of goals, and proper execution of project plans.
- Proactively identify potential project risks and bottlenecks, escalating issues when necessary and working to resolve them before they lead to delays.
- Track and manage project budgets, ensuring that all activities are completed within the allocated budget, and providing regular financial updates to leadership.
- Ensure that preclinical development activities are aligned with regulatory requirements, facilitating a smooth transition to IND filing.
- Maintain comprehensive project documentation and prepare reports to provide clear communication of project status, risks, and outcomes to senior management and other stakeholders.
Required Skills and Experience
- B.S. in Biology, Chemistry, Pharmacology, or related fields required; M.S. or Ph.D. preferred. PMP Certification is a plus but not required.
- B.S. with 5+ years of experience or M.S./Ph.D. with 3+ years of scientific project management experience in the pharmaceutical or biotech industries, with experience overseeing/coordinating preclinical development activities through IND filing.
- Proven ability to manage complex R&D projects, including experience with timeline management, risk identification, and issue escalation.
- Experience coordinating activities with CROs and external partners, including contract negotiations and performance management.
- Familiarity with the regulatory requirements and processes involved in IND filing, and experience ensuring compliance with these standards during preclinical development.
- Excellent written and verbal communication skills, with the ability to clearly articulate project progress, risks, and recommendations to cross-functional teams and leadership.
- Experience with project management software(e.g., Microsoft Project or similar)
Compensation
- Salary dependent on experience
- Annual performance bonus
- Equity incentive plan
Benefits
- Medical, Dental and Vision insurance
- 401K with company match
- Paid parental leave benefits
- Commuter benefit
- Building amenities including 24h fitness center access and roof top lounge
Grove Biopharma is an equal opportunity employer. We celebrate diversity and are committed to an inclusive work environment for all employees.
Interested applicants should send CV/resume and cover letter (~1 page) to careers@grovebiopharma.com.
ABOUT
Grove Biopharma is a biotechnology company pioneering its proprietary Bionic Biologics™ platform to develop novel therapies targeting intracellular protein-protein interactions. Bionic Biologics represent a novel therapeutic modality that integrates principles of biologic and synthetic design to create customizable protein-scale molecules. This innovative platform enables the targeting of well-validated yet previously intractable disease drivers, unlocking new possibilities for therapeutic intervention.
Job DescriPtion
We are seeking an experienced Senior Scientist in Bioanalytical Chemistry to join our research and development team. This position plays a critical role in advancing our understanding of drug behavior in biological systems through the development and application of cutting-edge bioanalytical techniques. The ideal candidate will have extensive experience in the analysis of biological samples using mass spectrometry and other high-throughput analytical methods. This position offers an exciting opportunity to contribute to the success of our drug discovery programs by developing and validating robust bioanalytical methods for complex biological matrices that can translate from preclinical use into clinical trials.
Key Responsibilities
- Develop and validate bioanalytical methods for the quantitative analysis of biological samples, ensuring the accuracy, sensitivity, and reproducibility of results.
- Utilize advanced mass spectrometry techniques to analyze biological samples, supporting pharmacokinetic, pharmacodynamic, and toxicological studies.
- Design and execute bioanalytical experiments, analyzing complex data sets to provide insights into the pharmacokinetics and metabolism of drug candidates.
- Work closely with cross-functional teams, including pharmacologists, toxicologists, and medicinal chemists, to integrate bioanalytical data into the broader drug development process.
- Oversee the maintenance and operation of bioanalytical instruments, ensuring that all equipment is calibrated and functioning optimally for high-throughput analysis.
Required Skills and Experience
- M.S. or Ph.D. in Bioanalytical Chemistry, Analytical Chemistry, or a closely related field.
- 5+ years of postdoctoral experience required for Ph.D., 10+ years of post-degree experience for M.S. level; experience in pharma or biotech industry strongly preferred.
- High level of expertise with LC/MS MS and other high-throughput analytical methods for the quantitative analysis of biological samples in complex matrices (e.g., serum, tissue, tumor); experience in bottoms-up proteomics workflows and the analysis of peptide-based modalities strongly preferred.
- Demonstrated ability to develop and validate bioanalytical methods, ensuring the precision and accuracy required for drug development studies.
- Excellent collaboration skills, with the ability to work effectively in a multidisciplinary team, and strong written and verbal communication skills for presenting complex scientific data.
Compensation
- Salary dependent on experience
- Annual performance bonus
- Equity incentive plan
Benefits
- Medical, Dental and Vision insurance
- 401K with company match
- Paid parental leave benefits
- Commuter benefit
- Building amenities including 24h fitness center access and roof top lounge
Grove Biopharma is an equal opportunity employer. We celebrate diversity and are committed to an inclusive work environment for all employees.
Interested applicants should send CV/resume and cover letter (~1 page) to careers@grovebiopharma.com.
